Tetramisole bolus 600mg For Animal Worms
tetramisole bolus 600mg for animal worms
For veterinary use only
COMPOSITION
Each tablet contains
Tetramisole...........600mg
INDICATION
for the treatment and contro of parasitic gastroenteritis and verminous bronchitis caused by round works(nematodes) in sheep, goats, cattle and camels. GASTR-INTESTINAL WORMS, LUNGWORMS
DOSAGE AND ADMINISTRATION
For oral administration.
single dose each time.
15 mg active substance per kg body weight.
lambs, kids: half bolus/20 kg body weight.
SHEEP, GOATS, CATTLE, CAMELS: 1 BOLUS/40KG BODY WEIGHT
WITHDRAWAL TIME:
for meat: 7 days
for milk:2 days
STORAGE
Seal and protect from the light.
Keep out of reach of children.
SHELF LIFE
3 years.
PHARMACOLOGICAL ACTION:
Pharmacodynamics This product is an imidazothiazole antinematode, which is active against most nematodes in cattle, sheep, pigs, dogs and chickens. Its anthelmintic mechanism is to excite the parasympathetic and sympathetic ganglia of the worm, which exhibits a nicotinic effect; at high concentrations, tetramisole interferes with the carbohydrate metabolism of the nematode by blocking the reduction of fumaric acid and the oxidation of succinate, and ultimately paralyzes the worm. The role of live worms to discharge.
In addition to its anthelmintic activity, this product can also significantly improve the immune response. It can restore the cell-mediated immune function of peripheral T lymphocytes, excite the phagocytosis of monocytes, and have a more obvious effect on animals with impaired immune function.
Pharmacokinetics This product can be absorbed from the gastrointestinal tract after oral administration. After absorption, it can be distributed throughout the body. Most of it is metabolized in the liver and kidneys. The metabolites are mainly excreted in urine. Less than 6% are excreted in their original form, and a small amount is excreted in feces. The plasma half-lives are 4 to 6 hours for cattle, 3 to 4 hours for sheep, 3.5 to 6.8 hours for pigs, and 1.8 to 4 hours for dogs.
Keep out of reach of children.
For Veterinary Use Only